A surgeon is interested in determining whether the administration of a certain drug can reduce the incidence of pulmonary embolism (PE- a blood clot in the lungs) in patients undergoing high-risk surgery. Nineteen patients were selected for the study, with 11 getting the drug and 8 receiving the standard treatment. Here are the data:
Experienced pulmonary embolism? Yes No Total Drug 3 8 11 No Drug 4 4 8 Total 7 12 19 (a) Estimate Rerug = the true probability of experiencing PE when taking the drug, and Rstandard true probability of PE when not taking the drug. (b) Does the treatment produce any change in the likelihood of PE? (c) After these data were analyzed, the surgeon asks for your help to plan another experiment to test a different drug for reducing incidence of PE. He believes it is effective, and tells you he thinks it is at least as good as this one, but this time wants to you to help him design an experiment that gives a good chance of proving that is true. He asks how large a sample he will need to do so. Determine the sample size for him.
You may need to ask him questions; if so, supply the questions and the answers. Then determine an adequate sample size. If you simply use software to obtain the answer, you will not receive credit for this problem. Rather, you must show how to carry out the computation providing the solutions you provide. If you must make an approximation or assumption, clearly explain what it is. Get Medicine Homework Help Today
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